Which motion may interrupt a speaker, does not require a second, and is amendable?

The motion that may interrupt a speaker, does not require a second, and is amendable is the motion to "Raise a Question of Privilege." This type of motion allows a member to address an urgent matter related to the rights and privileges of the assembly or its members, such as a request for better room conditions or to address personal discomfort.

It is significant because this motion can be made at any time, even while another member is speaking, which is an essential feature distinguishing it. Furthermore, since it deals with the immediate rights of members, it does not require a second, underscoring its urgency. While it is generally not amendable, the options provided do not accurately reflect this specific motion's attributes; however, it clearly illustrates why the other selections do not fit the criteria as well. This knowledge enhances understanding of parliamentary procedure and emphasizes the importance of recognizing different types of motions within a meeting context.